Will I get rejected by UC's if I have D's and F's even if my gpa is above 3.0?

Can I get into a UC (Irvine, LA, SD, etc) if I have a D in American Sign Language, a college course which counts for 2 semesters, and two F's in spanish, even if my GPA is above 3.0? Or is a D/F mean I am automatically rejected from all UC's?